Rabbit Anti-MAP4K3/GLK antibody

Home > Product > Antibody > Rabbit Anti-MAP4K3/GLK antibody

Germinal center kinase like kinase; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1.

Cat:

SL18666R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MAP4K3/GLK:261-360/894

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Function:
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Subunit:
Interacts with SH3GL2. Interaction appears to regulate MAP4K3-mediated JNK activation

Subcellular Location:
Cytoplasmic and Nuclear

Tissue Specificity:
Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.

Similarity:
Belongs to the protein kinase superfamily.
STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 CNH domain.
Contains 1 protein kinase domain.

SWISS:
Q8IVH8

Gene ID:
8491

Database links:

Entrez Gene: 8491 Human

Entrez Gene: 225028 Mouse

Entrez Gene: 170920 Rat

Omim: 604921 Human

SwissProt: Q8IVH8 Human

SwissProt: Q99JP0 Mouse

SwissProt: Q924I2 Rat

Product Feedback Wall