Rabbit Anti-MAN2B2 antibody

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EC 3.2.1.24; Laman; Lysosomal acid alpha mannosidase; Lysosomal alpha mannosidase; MANB; Mannosidase alpha class 2B member 1; Mannosidase, alpha B; Mannosidase, alpha B.

Cat:

SL18648R

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human MAN2B2:581-680/1009

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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MAN2B2 is a 1,009 amino acid secreted protein that belongs to the glycosyl hydrolase 38 family. Expressed as multiple alternatively spliced isoforms, MAN2B2 uses zinc as a cofactor to catalyze the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannoside proteins. The gene encoding MAN2B2 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Subcellular Location:
Secreted

SWISS:
Q9Y2E5

Gene ID:
23324

Database links:

Entrez Gene: 23324 Human

SwissProt: Q9Y2E5 Human

Unigene: 188464 Human

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