Rabbit Anti-MAN1C1 antibody

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1 2 alpha mannosidase IC; Alpha 1 2 mannosidase IC; HMIC; MAN1A3; MAN1C; Mannosidase alpha class 1C member 1; Mannosyl oligosaccharide 1 2 alpha mannosidase IC; pp6318; Processing alpha 1 2 mannosidase IC.

Cat:

SL18645R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human MAN1C1:151-250/630

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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MAN1C1 belongs to the glycosyl hydrolase 47 family. It is involved in the maturation of Asn-linked oligosaccharides. It trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. MAN1C1 is expressed in most tissues with the exception of lung, muscle and pancreas. It is highly expressed in placenta.

Function:
Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce first Man8GlcNAc2 then Man6GlcNAc and a small amount of Man5GlcNAc.

Tissue Specificity:
Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta.

Similarity:
Golgi apparatus membrane; Single-pass type II membrane protein.

SWISS:
Q9NR34

Gene ID:
57134

Database links:

Entrez Gene: 57134 Human

SwissProt: Q9NR34 Human

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