Rabbit Anti-MAGEA8 antibody

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Cancer/testis antigen 1.8; CT1.8; MAGA8_HUMAN; MAGE 8 antigen; MAGE-8 antigen; MAGE8 antigen; MAGEA8; Melanoma antigen family A 8; Melanoma associated antigen 8; Melanoma-associated antigen 8; MGC2182.

Cat:

SL18619R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human MAGEA8:1-100/318

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]

Function:
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Tissue Specificity:
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testis and placenta.

Similarity:
Contains 1 MAGE domain.

SWISS:
P43361

Gene ID:
4107

Database links:

Entrez Gene: 4107 Human

Omim: 300341 Human

SwissProt: P43361 Human

Unigene: 522803 Human

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