background:
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis. [provided by RefSeq, Dec 2010]
Function:
Acts as a co-chaperone with an Hsp70 protein.
Subcellular Location:
Cytoplasm. Nucleus. Stress induces its translocation to the nucleus.
Similarity:
Contains 1 J domain.
Database links:
Entrez Gene: 4189 Human
Entrez Gene: 744984 Chimpanzee
Entrez Gene: DNAJB9 Cow
Entrez Gene: 475286 Dog
Entrez Gene: 27362 Mouse
Entrez Gene: 24908 Rat
Omim: 602634 Human
SwissProt: Q9UBS3 Human
SwissProt: Q9QYI6 Mouse
SwissProt: P97554 Rat
Unigene: 6790 Human
Unigene: 27432 Mouse
Unigene: 29778 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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