Rabbit Anti-DNAJA4/FITC Conjugated antibody

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DnaJ (Hsp40) homolog subfamily A member 4; DnaJ (Hsp40) homolog, subfamily A, member4; DNAJ A4; DnaJ homolog subfamily A member 4; DNAJA 4; DNAJA4; DNJA4_HUMAN; MST104; MSTP104; PRO1472.

Cat:

SL14368R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DNAJA4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.

Subcellular Location:
Membrane.

Similarity:
Contains 1 CR-type zinc finger.
Contains 1 J domain.

Database links:

Entrez Gene: 55466 Human

Entrez Gene: 528615 Cow

Entrez Gene: 58233 Mouse

Entrez Gene: 397613 Pig

Entrez Gene: 300721 Rat

SwissProt: Q8WW22 Human

SwissProt: Q9JMC3 Mouse

Unigene: 513053 Human

Unigene: 489676 Mouse

Unigene: 228618 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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