Rabbit Anti-CXX1/FITC Conjugated antibody

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Cerebral protein 5; CAAX box protein 1; CXX 1; FAM127A; Family with sequence similarity 127, member A; Mammalian retrotransposon derived protein 8C; Mar8; MAR8C; Mart8; MART8C; CXX1_HUMAN.

Cat:

SL14125R-FITC

Species Reactivity：

Human,

Immunogen：

KLH conjugated synthetic peptide derived from human Cerebral protein 5/CXX1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

22kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The CXX1 gene product has been provisionally designated CXX1 pending further characterization.

Function:
There seems to be two proteins that can be transcribed from FAM127A, one with a C terminal CAAX box (Swissprot id O15255) and a smaller protein (AC A6ZKI3) that seems to be encoded by a multicopy gene originating from a retrotransposon.

Subcellular Location:
Cell membrane; Lipid anchor

Tissue Specificity:
Ubiquitous.

Database links:

Entrez Gene: 8933 Human

Omim: 300213 Human

SwissProt: A6ZKI3 Human

SwissProt: O15255 Human

Unigene: 522789 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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