Rabbit Anti-Troponin T fast + slow skeletal muscle/FITC Conjugated antibody

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AMCD2B; Beta TnTF; Beta-TnTF; DA2B; DKFZp779M2348; fast skeletal muscle; Fast skeletal muscle troponin T; FSSV; fTnT; TNNT 3; Tnnt3; TNNT3_HUMAN; TnTf; Troponin T; Troponin T fast skeletal muscle; Troponin T type 3 (skeletal fast); Troponin T type 3; Trop

Cat:

SL10620R-FITC

Species Reactivity：

(predicted: Human,Chicken,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Troponin T fast + slow skeletal muscle

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

32kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Tissue Specificity:
In fetal and adult fast skeletal muscles, with a higher level expression in fetal than in adult muscle.

DISEASE:
Defects in TNNT3 are a cause of distal arthrogryposis type 2B (DA2B) [MIM:60336]; also known as arthrogryposis multiplex congenita, distal, type 2B (AMCD2B). DA2B is a form of inherited multiple congenital contractures. Affected individuals have vertical talus, ulnar deviation in the hands, severe camptodactyly, and a distinctive face characterized by a triangular shape, prominent nasolabial folds, small mouth and a prominent chin.

Similarity:
Belongs to the troponin T family.

Database links:

Entrez Gene: 7140 Human

Entrez Gene: 21957 Mouse

Entrez Gene: 24838 Rat

Omim: 600692 Human

SwissProt: P45378 Human

SwissProt: Q9QZ47 Mouse

SwissProt: P09739 Rat

Unigene: 73454 Human

Unigene: 389992 Mouse

Unigene: 15488 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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